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1

In Vivo Toxicity, Pharmacokinetic Features, and Immunogenicity of B43(Anti-CD19)-Genistein Immunoconjugate in Mice and Non-human Primates

MYERS, DOROTHEA E., UCKUN, FATIH M.

Journal:

Journal of Medicinal Food

Year:

1999

Language:

english

File:

PDF, 2.98 MB

english, 1999

2

Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL

Uckun, Fatih M., Mitchell, Lloyd G., Qazi, Sanjive, Liu, Yang, Zheng, Nan, Myers, Dorothea E., Song, Ziyuan, Ma, Hong, Cheng, Jianjun

Journal:

Year:

2015

Language:

english

File:

PDF, 2.22 MB

english, 2015

3

The enzymatic synthesis of some potential photoaffinity analogs of benzoyl-coenzyme A

Dorothea E. Myers, Merton F. Utter

Journal:

Analytical Biochemistry

Year:

1981

Language:

english

File:

PDF, 966 KB

english, 1981

4

Inhibition of HIV-1 replication in seropositive patients' CD4+ T-cells by pokeweed antiviral protein-monoclonal antibody conjugates

Joyce M. Zarling, Patricia A. Moran, Omar Haffar, Michael Diegel, Dorothea E. Myers, Virginia Kuelbeck, Jeffrey A. Ledbetter, Fatih M. Uckun

Journal:

International Journal of Immunopharmacology

Year:

1991

Language:

english

File:

PDF, 396 KB

english, 1991

5

Inhibition of HIV replication by pokeweed antiviral protein targeted to CD4+ cells by monoclonal antibodies

Zarling, Joyce M., Moran, Patricia A., Haffar, Omar, Sias, Joan, Richman, Douglas D., Spina, Celsa A., Myers, Dorothea E., Kuebelbeck, Virginia, Ledbetter, Jeffrey A., Uckun, Fatih M.

Journal:

Year:

1990

File:

PDF, 753 KB

1990

6

Anti-CD2 (T, p50) intact ricin immunotoxins for GVHD-prophylaxis in allogeneic bone marrow transplantation

Fatih M. Uckun, Susan M. Azemove, Dorothea E. Myers, Daniel A. Vallera

Journal:

Leukemia Research

Year:

1986

Language:

english

File:

PDF, 743 KB

english, 1986

7

A soluble transhydrogenase enzyme from Rhodospirillum rubrum chromatophores

Dorothea E. Myers, Richard J. Guillory

Journal:

Year:

1974

Language:

english

File:

PDF, 207 KB

english, 1974

8

The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins

Dorothea E. Myers, Fatih M. Uckun, Steven E. Swaim, Daniel A. Vallera

Journal:

Journal of Immunological Methods

Year:

1989

Language:

english

File:

PDF, 1.03 MB

english, 1989

9

Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials

Dorothea E. Myers, James D. Irvin, Ron S. Smith, Virginia M. Kuebelbeck, Fatih M. Uckun

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 1.30 MB

english, 1991

10

The role of host RNA polymerase in P1 phage development

Dorothea E. Myers, Arthur Landy

Journal:

Year:

1973

Language:

english

File:

PDF, 389 KB

english, 1973

11

In Vitro and in Vivo Anti-Leukemic Efficacy of Cyclic AMP Modulating Agents Against Human Leukemic B-cell Precursors

Myers, Dorothea E., Chandan-Langlie, Mridula, Chelstrom, Lisa M., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1996

Language:

english

File:

PDF, 488 KB

english, 1996

12

Engagement of the CD19 Receptor on Human B-Lineage Leukemia Cells Activates LCK Tyrosine Kinase and Facilitates Radiation-Induced Apoptosis

Kevin G. Waddick, HeonJoo Park Chae, Lisa Tuel-Ahlgren, Lisa J. Jarvis, Ilker Dibirdik, Dorothea E. Myers and Fatih M. Uckun

Journal:

Radiation Research

Year:

1993

Language:

english

File:

PDF, 1.54 MB

english, 1993

13

Activation of yeast pyruvate carboxylase: interactions between acyl coenzyme A compounds, aspartate, and substrates of the reaction

Myers, Dorothea E., Tolbert, Bernadine, Utter, Merton F.

Journal:

Year:

1983

Language:

english

File:

PDF, 830 KB

english, 1983

14

CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells

Myers, Dorothea E., Yiv, Seang, Qazi, Sanjive, Ma, Hong, Cely, Ingrid, Shahidzadeh, Anoush, Arellano, Martha, Finestone, Erin, Gaynon, Paul S., Termuhlen, Amanda, Cheng, Jianjun, Uckun, Fatih M.

Journal:

Integrative Biology

Year:

2014

Language:

english

File:

PDF, 3.49 MB

english, 2014

15

Allograft and Autograft Purging Using Immunotoxins in Clinical Bone Marrow Transplantation for Hematologic Malignancies

UCKUN, FATIH M., MYERS, DOROTHEA E.

Journal:

Journal of Hematotherapy

Year:

1993

Language:

english

File:

PDF, 1.30 MB

english, 1993

16

Low Dose Total Body Irradiation Combined With Recombinant CD19-Ligand×Soluble TRAIL Fusion Protein is Highly Effective Against Radiation-resistant B-precursor Acute Lymphoblastic Leukemia in Mice

Uckun, Fatih M., Myers, Dorothea E., Ma, Hong, Rose, Rebecca, Qazi, Sanjive

Journal:

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

17

CD22 ΔE12 as a molecular target for RNAi therapy

Uckun, Fatih M., Ma, Hong, Cheng, Jianjun, Myers, Dorothea E., Qazi, Sanjive

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

18

Effects of the Intermolecular Toxin-Monoclonal Antibody Linkage on the In Vivo Stability, Immunogenicity and Anti-Leukemic Activity of B43 (Anti-CD19) Pokeweed Antiviral Protein Immunotoxin

Uckun, Fatih M., Myers, Dorothea E., Irvin, James D., Kuebelbeck, Virginia M., Finnegan, Dale, Chelstrom, Lisa M., Houston, L. L.

Journal:

Leukemia and Lymphoma

Year:

1993

Language:

english

File:

PDF, 1.51 MB

english, 1993

19

An Anti-CD72 Immunotoxin Against Therapy-Refractory B-Lineage Acute Lymphoblastic Leukemia

Myers, Dorothea E., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1995

Language:

english

File:

PDF, 424 KB

english, 1995

20

Favorable Pharmacodynamic Features and Superior Anti-Leukemic Activity of B43 (Anti-CD 19) Immunotoxins Containing Two Pokeweed Antiviral Protein Molecules Covalently Linked to each Monoclonal Antibody Molecule

Myers, Dorothea E., Yanishevski, Yuri, Masson, Eric, Irvin, James D., Evans, William E., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

21

Role of Hydroxyl Radicals in Radiation-Induced Activation of Lyn Tyrosine Kinase in Human B-Cell Precursors

Xiao, Jun, Biaglow, John E., Chae-Park, Hean-Joo, Jin, Jizhong, Tuel-Ahlgren, Lisa, Myers, Dorothea E., Burkhardt, Anne L., Bolen, Joseph B., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1996

Language:

english

File:

PDF, 1.53 MB

english, 1996

22

Large Scale Manufacturing of B43(Anti-CD19)-Genistein for Clinical Trials in Leukemia and Lymphoma

Myers, Dorothea E., Sicheneder, Andrew, Clementson, Dina, Dvorak, Nancy, Venkatachalam, Taracad, Sev, Alexander Rostov, Chandan-Langlie, Mridula, Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1998

Language:

english

File:

PDF, 2.13 MB

english, 1998

23

Treatment of Human B-Cell Precursor Leukemia in SCID Mice by Using a Combination of the Anti-CD19 Immunotoxin B43-PAP with the Standard Chemotherapeutic Drugs Vincristine, Methylprednisolone, and L-Asparaginase

Ek, Onur, Gaynon, Paul, Zeren, Tamer, Chelstrom, Lisa M., Myers, Dorothea E., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1998

Language:

english

File:

PDF, 673 KB

english, 1998

24

Membrane-Associated CD19-LYN Complex is an Endogenous p53-Independent and Bcl-2-Independent Regulator of Apoptosis in Human B-Lineage Lymphoma Cells

Dorothea E. Myers, Xiao Jun, Kevin G. Waddick, Craig Forsyth, Lisa M. Chelstrom, Roland L. Gunther, Nilgun E. Tumer, Joseph Bolen and Fatih M. Uckun

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.25 MB

english, 1995

25

Isolation and Characterization of Dihydrodipicolinate Synthase from Maize

David A. Frisch, Burle G. Gengenbach, Andrew M. Tommey, Janita M. Sellner, David A. Somers and Dorothea E. Myers

Journal:

PLANT PHYSIOLOGY

Year:

1991

Language:

english

File:

PDF, 1.21 MB

english, 1991

26

Correction: Tyrosine Phosphorylation is a Mandatory Proximal Step in Radiation-Induced Activation of the Protein Kinase C Signaling Pathway in Human B-Lymphocyte Precursors

Faith M. Uckun, Gary L. Schieven, Lisa M. Tuel-Ahlgren, Ilker Dibirdik, Dorothea E. Myers, Jeffrey A. Ledbetter and Chang W. Song

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 178 KB

english, 1993

27

Ionizing Radiation Stimulates Unidentified Tyrosine-Specific Protein Kinases in Human B-Lymphocyte Precursors, Triggering Apoptosis and Clonogenic Cell Death

Faith M. Uckun, Lisa Tuel-Ahlgren, Chang W. Song, Kevin Waddick, Dorothea E. Myers, Jean Kirihara, Jeffrey A. Ledbetter and Gary L. Schieven

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.26 MB

english, 1992

28

Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice

Uckun, Fatih M., Myers, Dorothea E., Cheng, Jianjun, Qazi, Sanjive

Journal:

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

29

IMMUNOTOXINS FOR EX VIVO MARROW PURGING IN AUTOLOGOUS BONE MARROW TRANSPLANTATION FOR ACUTE NONLYMPHOCYTIC LEUKEMIA

MYERS, DOROTHEA E., UCKUN, FATIH M., BALL, EDWARD D., VALLERA, DANIEL A.

Journal:

Transplantation Journal

Year:

1988

File:

PDF, 663 KB

1988

30

Large Scale Manufacturing of TXU(Anti-CD7)-Pokeweed Antiviral Protein (PAP) Immunoconjugate for Clinical Trials

Myers, Dorothea E., Jun, Xiao, Clementson, Dina, Donelson, Randy, Sicheneder, Andrew, Hoffman, Nathan, Bell, Kim, Sarquis, Mireille, Langlie, Mridula-Chandan, Turner, Nilgun, Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1997

Language:

english

File:

PDF, 2.45 MB

english, 1997

31

Tyrosine Phosphorylation is a Mandatory Proximal Step in Radiation-Induced Activation of the Protein Kinase C Signaling Pathway in Human B-Lymphocyte Precursors

Fatih M. Uckun, Gary L. Schieven, Lisa M. Tuel-Ahlgren, Ilker Dibirdik, Dorothea E. Myers, Jeffrey A. Ledbetter and Chang W. Song

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

32

Recombinant human CD19L-sTRAIL effectively targets B cell precursor acute lymphoblastic leukemia

Uckun, Fatih M., Myers, Dorothea E., Qazi, Sanjive, Ozer, Zahide, Rose, Rebecca, D’Cruz, Osmond J., Ma, Hong

Journal:

Journal of Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 3.32 MB

english, 2015

33

Combined Therapeutic Efficacy of the Thymidylate Synthase Inhibitor ZD1694 (TOMUDEX) and the Immunotoxin B43(Anti-CD19)-PAP in a SCID Mouse Model of Human B-Lineage Acute Lymphoblastic Leukemia

Ek, Onur, Reaman, Gregory H., Crankshaw, Daune L., Chelstrom, Lisa M., Myers, Dorothea E., Uckun, Fatih M.

Journal:

Leukemia and Lymphoma

Year:

1998

Language:

english

File:

PDF, 647 KB

english, 1998

34

Clinical Pharmacokinetics of the CD19 Receptor-Directed Tyrosine Kinase Inhibitor B43-Genistein in Patients with B-Lineage Lymphoid Malignancies

Chen, Chun-Lin, Levine, Alexandra, Rao, Asha, O'Neill, Karen, Messinger, Yoav, Myers, Dorothea E., Goldman, Frederick, Hurvitz, Carole, Casper, James T., Uckun, Fatih M.

Journal:

Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

35

Complications of Antiretroviral Therapy Initiation in Hospitalised Patients with HIV-Associated Tuberculosis

van der Plas, Helen, Meintjes, Graeme, Schutz, Charlotte, Goliath, Rene, Myer, Landon, Baatjie, Dorothea, Wilkinson, Robert J., Maartens, Gary, Mendelson, Marc, Braitstein, Paula

Journal:

Year:

2013

Language:

english

File:

PDF, 185 KB

english, 2013

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